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Propargyl-PEG4-CH2CH2-Boc

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Chemical Structure| 1245823-50-0 同义名 : -
CAS号 : 1245823-50-0
货号 : A177824
分子式 : C18H32O7
纯度 : 95%
分子量 : 360.442
MDL号 : MFCD22201534
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Propargyl-PEG4-CH2CH2-Boc, a non-cleavable ADC linker, is applicable in the creation of ADC inhibitors targeting Galectin-3. Additionally, this PEG- and Alkyl/ether-derived PROTAC linker is suitable for PROTAC synthesis[1]. Propargyl-PEG4-CH2CH2-Boc, a reagent for click chemistry, features an Alkyne group capable of engaging in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide group-containing molecules.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.77mL

0.55mL

0.28mL

13.87mL

2.77mL

1.39mL

27.74mL

5.55mL

2.77mL

参考文献

[1]Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275.