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Ezatiostat HCl

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Chemical Structure| 286942-97-0 同义名 : TER199;TLK199 hydrochloride;Ezatiostat hydrochloride
CAS号 : 286942-97-0
货号 : A170237
分子式 : C27H36ClN3O6S
纯度 : 98+%
分子量 : 566.109
MDL号 : MFCD03701300
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Ezatiostat hydrochloride is a glutathione analog inhibitor of glutathione S-transferase P1-1 (GSTP1-1).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.77mL

0.35mL

0.18mL

8.83mL

1.77mL

0.88mL

17.66mL

3.53mL

1.77mL
参考文献

[1]Raza A, Galili N, et al. Phase 1 dose-ranging study of ezatiostat hydrochloride in combination with lenalidomide in patients with non-deletion (5q) low to intermediate-1 risk myelodysplastic syndrome (MDS). J Hematol Oncol. 2012 Apr 30;5:18.

[2]Raza A, Galili N, et al. Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome. Blood. 2009 Jun 25;113(26):6533-40.