Aleplasinin

产品说明书

Print
Chemical Structure| 481629-87-2 同义名 : PAZ-417
CAS号 : 481629-87-2
货号 : A1671438
分子式 : C28H27NO3
纯度 : 99%+
分子量 : 425.51
MDL号 : -
存储条件：

Pure form Keep in dark place,Sealed in dry,Store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(587.53 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Aleplasinin is an orally active, potent, and BBB-permeable SERPINE1 (PAI-1) inhibitor that increases amyloid-β (Aβ) catabolism, reduces amyloid-related pathology, and improves memory deficits. It is applicable for Alzheimer's disease research[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.24mL

11.75mL

2.35mL

1.18mL

23.50mL

4.70mL

2.35mL
参考文献

[1]Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.