产品说明书

360A

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Chemical Structure| 794458-56-3 同义名 : -
CAS号 : 794458-56-3
货号 : A166038
分子式 : C27H23N5O2
纯度 : 98+%
分子量 : 449.504
MDL号 : MFCD26142927
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 360A is a strong affinity and selectivity inhibitor of G-quadruplex structures.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.22mL

0.44mL

0.22mL

11.12mL

2.22mL

1.11mL

22.25mL

4.45mL

2.22mL

参考文献

[1]Gauthier LR, Granotier C, et al. Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. Cell Mol Life Sci. 2012 Feb;69(4):629-40.

[2]Pennarun G, Granotier C, et al. Role of ATM in the telomere response to the G-quadruplex ligand 360A. Nucleic Acids Res. 2008 Mar;36(5):1741-54.