产品说明书

	同义名 :	-
	CAS号 :	30123-17-2
	货号 :	A165989
	分子式 :	C21H24ClN2NaO4S
	纯度 :	99%
	分子量 :	458.934
	MDL号 :	MFCD00879851
	存储条件：	粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Tianeptine sodium salt enhances 5-HT (serotonin) uptake selectively and shows no binding affinity for a broad spectrum of receptors, including serotonin and dopamine (IC50 >10 μM), nor does it affect noradrenaline or dopamine uptake. It is known for its antidepressant, anxiolytic, analgesic, and neuroprotective properties[1].[2].[3].[4].

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.18mL 0.44mL 0.22mL	10.89mL 2.18mL 1.09mL	21.79mL 4.36mL 2.18mL

参考文献

[1]Broqua P; Baudrie V; Chaouloff F Differential effects of the novel antidepressant tianeptine on L-5-hydroxytryptophan (5-HTP)-elicited corticosterone release and body weight loss. Eur Neuropsychopharmacol. 1992 Jun;2(2):115-20. [2]Alamo C, et, al. Tianeptine, an atypical pharmacological approach to depression. Rev Psiquiatr Salud Ment. Jul-Sep 2019;12(3):170-186. [3]Uzbay IT, et, al. Analgesic effect of tianeptine in mice. Life Sci. 1999;64(15):1313-9. [4]Plaisant F, et, al. Neuroprotective properties of tianeptine: interactions with cytokines. Neuropharmacology. 2003 May;44(6):801-9.