Chelerythrine

产品说明书

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Chemical Structure| 34316-15-9 同义名 : Toddaline;Broussonpapyrine
CAS号 : 34316-15-9
货号 : A164459
分子式 : C21H18NO4
纯度 : 99%+
分子量 : 348.372
MDL号 : MFCD00270393
存储条件：

Pure form Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Chelerythrine, a natural product isolated and purified from the herbs of Chelidonium majus with potent antimanic, antiproliferatvie and antitumor effect, can inhibit telomerase activity, and is a well-known protein kinase C inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.87mL

0.57mL

0.29mL

14.35mL

2.87mL

1.44mL

28.70mL

5.74mL

2.87mL
参考文献

[1]Vieira SM, de Oliveira VH, et al. Chelerythrine inhibits the sarco/endoplasmic reticulum Ca(2+)-ATPase and results in cell Ca(2+) imbalance. Arch Biochem Biophys. 2015 Mar 15;570:58-65.

[2]Ghosh S, Jana J, et al. Plant alkaloid chelerythrine induced aggregation of human telomere sequence--a unique mode of association between a small molecule and a quadruplex. Biochemistry. 2015 Feb 3;54(4):974-86.