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Crassicauline A

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Chemical Structure| 79592-91-9 同义名 : Crassicaulin A;3-Deoxyyunaconitine
CAS号 : 79592-91-9
货号 : A163976
分子式 : C35H49NO10
纯度 : 98+%
分子量 : 643.764
MDL号 : -
存储条件：

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(163.1 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Crassicauline A, a natural product isolated and purified from the roots of Aconitum transsectum Diels, possesses feeding deterrent activity against T. castaneum adults, with EC(50) values of 1134.5 ppm, and has analgesic activity with an ED50 of 0.048 mg/kg.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.55mL

0.31mL

0.16mL

7.77mL

1.55mL

0.78mL

15.53mL

3.11mL

1.55mL
参考文献

[1]Ka-Wing Chung K, Pak-Lam Chen S, et al. Measurement of yunaconitine and crassicauline A in small-volume blood serum samples by LC-MS/MS: tracing of aconite poisoning in clinical diagnosis. Talanta. 2012 Aug 15;97:491-8.

[2]Liu ZL, Cao J, et al. Feeding deterrents from Aconitum episcopale roots against the red flour beetle, Tribolium castaneum. J Agric Food Chem. 2011 Apr 27;59(8):3701-6.