FT709

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Chemical Structure| 2413991-74-7 同义名 : -
CAS号 : 2413991-74-7
货号 : A1600990
分子式 : C23H22N4O7S
纯度 : 98%
分子量 : 498.508
MDL号 : N/A
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(210.63 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 FT709 is a potent and selective inhibitor of USP9X, with an IC50 of 82 nM. USP9X is associated with centrosome function, chromosome alignment during mitosis, EGFR degradation, chemo-sensitization, and regulation of circadian rhythms[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.01mL

0.40mL

0.20mL

10.03mL

2.01mL

1.00mL

20.06mL

4.01mL

2.01mL
参考文献

[1]Clancy A, et, al. The deubiquitylase USP9X controls ribosomal stalling. J Cell Biol. 2021 Mar 1;220(3):e202004211.