生物活性 | |||
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描述 | Tz-Thalidomide, labeled with a tetrazine group, is a variant of Thalidomide. It exhibits binding affinity for BRD4, with IC50 values of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Containing a tetrazine moiety, Tz-Thalidomide can undergo iEDDA reactions with molecules that have a TCO group, making it a viable click chemistry reagent[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.75mL 0.35mL 0.17mL |
8.75mL 1.75mL 0.87mL |
17.50mL 3.50mL 1.75mL |
参考文献 |
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