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GSK-3β inhibitor 14

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Chemical Structure| 863004-48-2 同义名 : -
CAS号 : 863004-48-2
货号 : A1598821
分子式 : C17H17NOS
纯度 : 99%+
分子量 : 283.388
MDL号 : -
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 GSK-3β inhibitor 14, a benzothiazepinone derivative, shows limited inhibition of GSK-3β with an IC50 over 100 μM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.53mL

0.71mL

0.35mL

17.64mL

3.53mL

1.76mL

35.29mL

7.06mL

3.53mL
参考文献

[1]Zhang P, et al. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Eur J Med Chem. 2013 Mar;61:95-103.