产品说明书

ZINC194100678

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Chemical Structure| 1995025-05-2 同义名 : -
CAS号 : 1995025-05-2
货号 : A1597312
分子式 : C10H13N5O
纯度 : 95%
分子量 : 219.243
MDL号 : N/A
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 ZINC194100678, a powerful PAK1 inhibitor with an IC50 of 8.37 μM, inhibits MDA-MB-231 cell proliferation and is applicable in anticancer research[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.56mL

0.91mL

0.46mL

22.81mL

4.56mL

2.28mL

45.61mL

9.12mL

4.56mL
参考文献

[1]Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220.