Acrivastine

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Chemical Structure| 87848-99-5 同义名 : BW825C;BW 0270C;BW A825C
CAS号 : 87848-99-5
货号 : A158908
分子式 : C22H24N2O2
纯度 : 99%+
分子量 : 348.438
MDL号 : MFCD00869830
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(143.5 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 1 mg/mL(2.87 mM)，配合低频超声，并水浴加热至45℃助溶
动物实验配方：
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01732510 Atopic Dermatitis Phase 1 Terminated(The study was prema... 展开 >>turely stopped due to business reasons.) 收起 << - -
NCT01732510 - Terminated(The study was prema... 展开 >>turely stopped due to business reasons.) 收起 << - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.87mL

0.57mL

0.29mL

14.35mL

2.87mL

1.43mL

28.70mL

5.74mL

2.87mL
参考文献

[1]Brogden RN, et al. Acrivastine. A review of its pharmacological properties and therapeutic efficacy in allergic rhinitis, urticaria and related disorders. Drugs. 1991 Jun;41(6):927-40.

[2]Gibbs TG, et al. Acrivastine in two doses compared with placebo in a multicentre, parallel group study for the treatment of seasonal allergic rhinitis. Br J Clin Pract. 1989 Jan;43(1):11-4.