产品说明书

Pinosylvin

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Chemical Structure| 22139-77-1 同义名 : 银松素 ;trans-3,5-Dihydroxystilbene
CAS号 : 22139-77-1
货号 : A155702
分子式 : C14H12O2
纯度 : 99%+
分子量 : 212.244
MDL号 : MFCD00210544
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(494.71 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Pinosylvin, a natural product isolated and purified from the herbs of Pinus yunnanensis, can induce autophagy via AMPK activation. Pinosylvin has anti-inflammatory activity, may be utilized as a phytotherapic agent for the prevention of cardiovascular inflammatory diseases.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.71mL

0.94mL

0.47mL

23.56mL

4.71mL

2.36mL

47.12mL

9.42mL

4.71mL
参考文献

[1]Park J, Pyee J, Park H. Pinosylvin at a high concentration induces AMPK-mediated autophagy for preventing necrosis in bovine aortic endothelial cells. Can J Physiol Pharmacol. 2014 Dec;92(12):993-9.

[2]Yeo SC, Luo W, et al. Quantification of pinosylvin in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pre-clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jul 15;931:68-74.