USP7-IN-8
产品说明书
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同义名 : | - |
| CAS号 : | 2009273-60-1 | |
| 货号 : | A1549755 | |
| 分子式 : | C21H21N3O2 | |
| 纯度 : | 99% | |
| 分子量 : | 347.41 | |
| MDL号 : | MFCD34167533 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,Store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 85 mg/mL(244.67 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | USP7-IN-8 (example 81) is a selective inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 1.4 μM in an Ub-Rho110 assay. It exhibits no activity against USP47 and USP5. USP7-IN-8 demonstrates anticancer effects[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.88mL 0.58mL 0.29mL |
14.39mL 2.88mL 1.44mL |
28.78mL 5.76mL 2.88mL |
| 参考文献 |
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[1]Robert Blake, et al. Usp7 inhibitor compounds and methods of use. US20160272588A1. |