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AA38-3

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Chemical Structure| 65815-76-1 同义名 : -
CAS号 : 65815-76-1
货号 : A1549735
分子式 : C12H14N2O4
纯度 : 99%+
分子量 : 250.251
MDL号 : MFCD00276294
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(199.8 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 AA38-3 is another serine hydrolase inhibitor, albeit with a more restricted scope of activity compared to AA26-9. It can inhibit three specific serine hydrolases: ABHD6, ABHD11, and FAAH. This selectivity may offer insights into designing targeted therapies or research tools for studying the physiological and pathological roles of these enzymes[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.00mL

0.80mL

0.40mL

19.98mL

4.00mL

2.00mL

39.96mL

7.99mL

4.00mL

参考文献

[1]Adibekian A, et, al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78.