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(2S)-Isoxanthohumol

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Chemical Structure| 70872-29-6 同义名 : (2S)-异黄腐酚 ;(2S)-Isoxanthohumol;(−)-Isoxanthohumol;(2S)-4',7-Dihydroxy-5-methoxy-8-prenylflavanone
CAS号 : 70872-29-6
货号 : A154019
分子式 : C21H22O5
纯度 : 99%+
分子量 : 354.396
MDL号 : MFCD21364779
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(296.28 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Isoxanthohumol, a natural polyphenol isolated and purified from the roots of Sophora flavescens Ait. with antioxidant, anti-inflammatory, and antiangiogenic properties, shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV), and seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.82mL

0.56mL

0.28mL

14.11mL

2.82mL

1.41mL

28.22mL

5.64mL

2.82mL
参考文献

[1]Gąsiorowska J, Teisseyre A, et al. Inhibition of Kv1.3 Channels in Human Jurkat T Cells by Xanthohumol and Isoxanthohumol. J Membr Biol. 2015 Aug;248(4):705-11.

[2]Zolnierczyk AK, Msczka WK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82.