产品说明书

NCRW0005-F05

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Chemical Structure| 342779-66-2 同义名 : -
CAS号 : 342779-66-2
货号 : A1524638
分子式 : C16H13F2NO2
纯度 : 98%
分子量 : 289.277
MDL号 : MFCD02324363
存储条件:

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(362.97 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 NCRW0005-F05 is a highly effective GPR139 antagonist, demonstrating an IC50 of 0.21 µM. It is applicable in studies concerning diabetes, obesity, and Parkinson's disease[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.46mL

0.69mL

0.35mL

17.28mL

3.46mL

1.73mL

34.57mL

6.91mL

3.46mL

参考文献

[1]Wang J, et al. High-throughput screening of antagonists for the orphan G-protein coupled receptor GPR139. Acta Pharmacol Sin. 2015 Jul;36(7):874-8.