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1alpha-Hydroxy VD4

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Chemical Structure| 143032-85-3 同义名 : 1α-Hydroxy vitamin D4
CAS号 : 143032-85-3
货号 : A151425
分子式 : C28H46O2
纯度 : 95%
分子量 : 414.664
MDL号 : MFCD00923273
存储条件:

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(120.58 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 1alpha-Hydroxy VD4 , a 1alpha (OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.41mL

0.48mL

0.24mL

12.06mL

2.41mL

1.21mL

24.12mL

4.82mL

2.41mL

参考文献

[1]Makishima M, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer. 1998;77:33-39