STING-IN-2

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Chemical Structure| 346691-38-1 同义名 : C-170
CAS号 : 346691-38-1
货号 : A1512670
分子式 : C15H16N2O4
纯度 : 99%+
分子量 : 288.29
MDL号 : MFCD00784211
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(416.25 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 STING-IN-2 (C-170) functions as a potent covalent inhibitor of both mouse STING (mmSTING) and human STING (hsSTING), and it can be employed in autoinflammatory disease [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.47mL

0.69mL

0.35mL

17.34mL

3.47mL

1.73mL

34.69mL

6.94mL

3.47mL
参考文献

[1]Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273.