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VH 032 amide-PEG1-acid

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Chemical Structure| 2172820-07-2 同义名 : -
CAS号 : 2172820-07-2
货号 : A1504747
分子式 : C28H38N4O7S
纯度 : 95%
分子量 : 574.689
MDL号 : N/A
存储条件:

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 VH032 amide-PEG1-acid (linker 10) is a VHL-1 alkyl linker employed to conjugate CDK4/6 ligands (PI) and degradation/destruction tags (EL) (e.g., E3 ligase ligands)[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.74mL

0.35mL

0.17mL

8.70mL

1.74mL

0.87mL

17.40mL

3.48mL

1.74mL

参考文献

[1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WIPO(PCT). WO2018106870A1. 2018-06-14.