产品说明书

Ipriflavone

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Chemical Structure| 35212-22-7 同义名 : 依普拉封;异普黄酮;依普瑞丰;易卜拉封;异丙黄酮 ;7-Isopropoxyisoflavone;Osteofix;TC 80;Yambolap;FL-113
CAS号 : 35212-22-7
货号 : A150093
分子式 : C18H16O3
纯度 : 98%
分子量 : 280.318
MDL号 : MFCD00221719
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 35 mg/mL(124.86 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:

IP 2% DMSO+2% Tween80+30% PEG300+water 1 mg/mL clear

PO 0.5% CMC-Na 67 mg/mL suspension

生物活性
描述 Ipriflavone is used to inhibit bone resorption.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.57mL

0.71mL

0.36mL

17.84mL

3.57mL

1.78mL

35.67mL

7.13mL

3.57mL

参考文献

[1]Miyata T, Notoya K, et al. Advanced glycation end products enhance osteoclast-induced bone resorption in cultured mouse unfractionated bone cells and in rats implanted subcutaneously with devitalized bone particles. J Am Soc Nephrol. 1997 Feb;8(2):260-70.

[2]Cheng SL, Zhang SF, et al. Stimulation of human osteoblast differentiation and function by ipriflavone and its metabolites. Calcif Tissue Int. 1994 Nov;55(5):356-62.