产品说明书

Mitiperstat

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Chemical Structure| 1933460-19-5 同义名 : AZD4831
CAS号 : 1933460-19-5
货号 : A1496425
分子式 : C15H15ClN4OS
纯度 : 98%+
分子量 : 334.824
MDL号 : N/A
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(358.4 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Mitiperstat (AZD4831) is a potent inhibitor of myeloperoxidase (MPO) and is particularly valuable in research aimed at the prophylaxis of cardiovascular disorders, including heart failure and coronary artery disease, as outlined in patent US20160152623A1[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.99mL

0.60mL

0.30mL

14.93mL

2.99mL

1.49mL

29.87mL

5.97mL

2.99mL
参考文献

[1]Tord Bertil INGHARDT, et al. 1-[2-(AMINOMETHYL)BENZYL]-2-THIOXO-1,2,3,5-TETRAHYDRO-4H-PYRROLO[3,2-d]PYRIMIDIN-4-ONES AS INHIBITORS OF MYELOPEROXIDASE. Patent US20160152623A1.