Orotic acid
产品说明书
 |
同义名 : | 6-Carboxyuracil;Vitamin B13 |
| CAS号 : | 65-86-1 | |
| 货号 : | A149396 | |
| 分子式 : | C5H4N2O4 | |
| 纯度 : | 98+% | |
| 分子量 : | 156.096 | |
| MDL号 : | MFCD00006027 | |
| 存储条件： |
Pure form Sealed in dry,Room Temperature In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 55 mg/mL(352.35 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Orotic acid, also known as 6-Carboxyuracil, serves as a precursor in the biosynthesis of pyrimidine nucleotides and RNA. It is released from mitochondrial dihydroorotate dehydrogenase (DHODH) and converted to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is utilized as a biomarker in routine newborn screening for urea cycle disorders and can induce hepatic steatosis and hepatomegaly in rats[1][2][3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
6.41mL 1.28mL 0.64mL |
32.03mL 6.41mL 3.20mL |
64.06mL 12.81mL 6.41mL |
| 参考文献 |
|---|