(S,R,S)-AHPC-amido-C5-acid
产品说明书
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同义名 : | - |
| CAS号 : | 2162120-87-6 | |
| 货号 : | A1471102 | |
| 分子式 : | C29H40N4O6S | |
| 纯度 : | 99%+ | |
| 分子量 : | 572.716 | |
| MDL号 : | MFCD32903593 | |
| 存储条件： |
Pure form Keep in dark place,Sealed in dry,Store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(183.34 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | (S,R,S)-AHPC-amido-C5-acid features a VHL ligand targeting the E3 ubiquitin ligase and acts as a PROTAC linker. It is utilized in creating XY028-133[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.75mL 0.35mL 0.17mL |
8.73mL 1.75mL 0.87mL |
17.46mL 3.49mL 1.75mL |
| 参考文献 |
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[1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1. |