CK7

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Chemical Structure| 507487-89-0 同义名 : -
CAS号 : 507487-89-0
货号 : A1466513
分子式 : C14H12N6O2S
纯度 : 99%
分子量 : 328.349
MDL号 : MFCD14585803
存储条件：

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 12 mg/mL(36.55 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 CK7 is a CDK2/9 inhibitor, and is also used to synthesise the Nek1 inhibitors BSc5231 and BSc5367[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.30mL

15.23mL

3.05mL

1.52mL

30.46mL

6.09mL

3.05mL
参考文献

[1]Pilakowski J, et al. Design, synthesis and biological evaluation of novel aminopyrazole- and 7-azaindole-based Nek1 inhibitors and their effects on zebrafish kidney development. Bioorg Med Chem Lett. 2021;53:128418.