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Berbamine

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Chemical Structure| 478-61-5 同义名 : BA;BBM
CAS号 : 478-61-5
货号 : A145417
分子式 : C37H40N2O6
纯度 : 99%
分子量 : 608.723
MDL号 : MFCD11501559
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(172.49 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.64mL

0.33mL

0.16mL

8.21mL

1.64mL

0.82mL

16.43mL

3.29mL

1.64mL
参考文献

[1]Parhi P, Suklabaidya S, et al. Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo. Sci Rep. 2017 Jul 19;7(1):5806.

[2]Zhao Y, Lv JJ, et al. Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis. Prostate Cancer Prostatic Dis. 2016 Dec;19(4):358-366.