产品说明书

Dapagliflozin impurity

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Chemical Structure| 960404-86-8 同义名 : -
CAS号 : 960404-86-8
货号 : A145381
分子式 : C21H25ClO7
纯度 : 99%+
分子量 : 424.872
MDL号 : MFCD32215328
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(58.84 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Dapagliflozin impurity is an enantiomer of Dapagliflozin, known as an inhibitor of the sodium-glucose transporter 2[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.24mL

11.77mL

2.35mL

1.18mL

23.54mL

4.71mL

2.35mL
参考文献

[1]Kasichayanula S, et al. Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects. Diabetes Obes Metab. 2011 Jan;13(1):47-54.