产品说明书

CX 717

Print
Chemical Structure| 867276-98-0 同义名 : -
CAS号 : 867276-98-0
货号 : A1446895
分子式 : C11H11N3O3
纯度 : 98%
分子量 : 233.223
MDL号 : N/A
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(214.39 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 CX 717 acts as a positive allosteric modulator of the AMPA receptor, demonstrating an antidepressant-like effect. It is applicable for studying adult attention deficit hyperactivity disorder (ADHD) [1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.29mL

0.86mL

0.43mL

21.44mL

4.29mL

2.14mL

42.88mL

8.58mL

4.29mL
参考文献

[1]Linda J Porrino, et al. Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates. PLoS Biol. 2005 Sep;3(9):e299.

[2]Marta Gordillo-Salas, et al. Antidepressant-Like Effects of CX717, a Positive Allosteric Modulator of AMPA Receptors. Mol Neurobiol. 2020 Aug;57(8):3498-3507.