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2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside

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Chemical Structure| 82373-94-2 同义名 : 芪多酚 ;TSG;trans-2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-Glucopyranoside;(E )-2,3,5,4′-Tetrahydroxystilbene-2-O-Glucoside;trans-2,3,5,4’-Tetrahydroxyl-diphenylethylene 2-O-β-D-Glucopyranoside;(E)-2,3,5,4’-Tetrahydroxyl-diphenylethylene 2-O-β-D-Glucoside;2,3,5,4'-Tetrahydroxyl-diphenylethylene 2-O-β-D-Glucoside;Astragalus polyphenols;2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside
CAS号 : 82373-94-2
货号 : A144286
分子式 : C20H22O9
纯度 : 99%+
分子量 : 406.383
MDL号 : MFCD00238694
存储条件:

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(258.38 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 10 mg/mL(24.61 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside is a natural product isolated and purified from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2, although less strongly.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.46mL

0.49mL

0.25mL

12.30mL

2.46mL

1.23mL

24.61mL

4.92mL

2.46mL

参考文献

[1]Zhang L, Yu S, et al. Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease. Restor Neurol Neurosci. 2013;31(1):41-52.

[2]Yu J, Xie J, et al. Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata. J Ethnopharmacol. 2011 Oct 11;137(3):1291-9.