产品说明书

KL201

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Chemical Structure| 302939-48-6 同义名 : -
CAS号 : 302939-48-6
货号 : A1440623
分子式 : C17H14BrN3OS
纯度 : 98%
分子量 : 388.282
MDL号 : N/A
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(643.86 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 KL201, a modulator of the circadian clock, selectively stabilizes isoform cryptochrome 1 (CRY1). However, it does not exert any stabilizing influence on CRY2. KL201 is effective in extending the period of circadian rhythms in both cellular and tissue contexts.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.58mL

0.52mL

0.26mL

12.88mL

2.58mL

1.29mL

25.75mL

5.15mL

2.58mL
参考文献

[1]Simon Miller, et al. An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals. Cell Chem Biol. 2020 Sep 17;27(9):1192-1198.e5.