Pachypodol

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Chemical Structure| 33708-72-4 同义名 : -
CAS号 : 33708-72-4
货号 : A141694
分子式 : C18H16O7
纯度 : 98+%
分子量 : 344.315
MDL号 : MFCD01937537
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(304.95 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Pachypodol, a natural product isolated and purified from the leaves of Calycopteris floribunda Lam., is the most active compound on ATP synthesis inhibition and inhibits the water-splitting enzyme activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.90mL

0.58mL

0.29mL

14.52mL

2.90mL

1.45mL

29.04mL

5.81mL

2.90mL
参考文献

[1]Arita M, Philipov S, Galabov AS. Phosphatidylinositol 4-kinase III beta is the target of oxoglaucine and pachypodol (Ro 09-0179) for their anti-poliovirus activities, and is located at upstream of the target step of brefeldin A. Microbiol Immunol. 2015 Jun;59(6):338-47.

[2]Ali HA, Chowdhury AK, et al. Pachypodol, a flavonol from the leaves of Calycopteris floribunda, inhibits the growth of CaCo 2 colon cancer cell line in vitro. Phytother Res. 2008 Dec;22(12):1684-7.