产品说明书

2-(Aminomethyl)phenol

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Chemical Structure| 932-30-9 同义名 : 2-Hydroxybenzylamine;o-Hydroxybenzylamine;NSC 127870;2-HOBA
CAS号 : 932-30-9
货号 : A140141
分子式 : C7H9NO
纯度 : 95%
分子量 : 123.153
MDL号 : MFCD00870498
存储条件:

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(406 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 2-(Aminomethyl)phenol, known for its selective dicarbonyl scavenging activity, functions as an antioxidant and a scavenger of free radicals and isolevuglandins (IsoLGs), with applications in studying inflammation and cardiovascular diseases, including atherosclerosis and atrial fibrillation (AF)[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

8.12mL

1.62mL

0.81mL

40.60mL

8.12mL

4.06mL

81.20mL

16.24mL

8.12mL

参考文献

[1]Matthew J O'Neill, et al. 2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device.

[2]Huan Tao, et al. Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr -/- mice.