产品说明书

Emapunil

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Chemical Structure| 226954-04-7 同义名 : AC-5216;XBD-173;18 kiloDalton Translocator Protein
CAS号 : 226954-04-7
货号 : A138931
分子式 : C23H23N5O2
纯度 : 98%
分子量 : 401.461
MDL号 : MFCD07772312
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(87.18 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Emapunil is a translocator protein [TSPO(18 kDa)] ligand.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.49mL

0.50mL

0.25mL

12.45mL

2.49mL

1.25mL

24.91mL

4.98mL

2.49mL
参考文献

[1]Qiu ZK, Zhang LM, et al. Repeated administration of AC-5216, a ligand for the 18 kDa translocator protein, improves behavioral deficits in a mouse model of post-traumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:40-6.

[2]Kita A, Kohayakawa H, et al. Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand. Br J Pharmacol. 2004 Aug;142(7):1059-72.