产品说明书
BCH001
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同义名 : | - |
| CAS号 : | 384859-58-9 | |
| 货号 : | A1374315 | |
| 分子式 : | C20H15F3N2O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 420.339 | |
| MDL号 : | MFCD02932975 | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 120 mg/mL(285.48 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | BCH001, a quinoline derivative, acts as a specific inhibitor of PAPD5. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. It exhibits no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is utilized for regulating aging [1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.38mL 0.48mL 0.24mL |
11.90mL 2.38mL 1.19mL |
23.79mL 4.76mL 2.38mL |
| 参考文献 |
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