(-)-Alkannin

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Chemical Structure| 517-88-4 同义名 : 紫草素 ;NSC 94524;Alkannin;(–)-Alkannin, NSC-94524, NSC94524. NSC 94524;(–)-Alkannin
CAS号 : 517-88-4
货号 : A1371256
分子式 : C16H16O5
纯度 : 99%+
分子量 : 288.295
MDL号 : MFCD00189414
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(121.4 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Alkannin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc., can suppress the cell viability, adhesion, invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.47mL

0.69mL

0.35mL

17.34mL

3.47mL

1.73mL

34.69mL

6.94mL

3.47mL
参考文献

[1]Liu JP, Liu D, et al. Shikonin inhibits the cell viability, adhesion, invasion and migration of the human gastric cancer cell line MGC-803 via the Toll-like receptor 2/nuclear factor-kappa B pathway. J Pharm Pharmacol. 2015 Aug;67(8):1143-55.

[2]Gara RK, Srivastava VK, et al. Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway. J Biomed Sci. 2015 Apr 1;22:26.