产品说明书

Dehydrodiisoeugenol

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Chemical Structure| 2680-81-1 同义名 : 去氢二异丁香酚
CAS号 : 2680-81-1
货号 : A1371141
分子式 : C20H22O4
纯度 : 99%+
分子量 : 326.386
MDL号 : N/A
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(321.7 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Dehydrodiisoeugenol, a natural product isolated and purified from the seeds of Myristica fragrans Houtt. with anti-inflammatory activity, inhibits LPS-stimulated expression of the COX-2 in RAW264.7 murine macrophages and phosphorylation-dependent proteolysis of inhibitor IκB-α and transcriptional activity of NF-κB in the cells, and can cross the blood-brain barrier rapidly and might be one of the main bioactive substances of nutmeg.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.06mL

0.61mL

0.31mL

15.32mL

3.06mL

1.53mL

30.64mL

6.13mL

3.06mL

参考文献

[1]Zhang YB, Zhu LQ, Yang XW. Cerebral nuclei distribution study of dehydrodiisoeugenol as an anxiogenic agent determined by RP-HPLC. Fitoterapia. 2013 Jan;84:47-53.

[2]Li F, Yang XW. Analysis of anti-inflammatory dehydrodiisoeugenol and metabolites excreted in rat feces and urine using HPLC-UV. Biomed Chromatogr. 2012 Jun;26(6):703-7.