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Prosapogenin A

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Chemical Structure| 19057-67-1 同义名 : Progenin III
CAS号 : 19057-67-1
货号 : A1371136
分子式 : C39H62O12
纯度 : 98+%
分子量 : 722.9
MDL号 : MFCD16294846
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(145.25 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Prosapogenin A, a natural product isolated and purified from the roots of Ophiopogon japonicus with anti-obesity and immunomodulating effect, exhibits cytotoxic activity against the cancer cell line K562 in vitro.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.38mL

0.28mL

0.14mL

6.92mL

1.38mL

0.69mL

13.83mL

2.77mL

1.38mL

参考文献

[1]Wang TX, Zhang ZQ, et al. Prosapogenin A induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis. Oncol Lett. 2013 Nov;6(5):1323-1328.

[2]Wang TX, Shi XY, et al. [Prosapogenin A inhibits cell growth of MCF7 via downregulating STAT3 and glycometabolism-related gene] . Yao Xue Xue Bao. 2013 Sep;48(9):1510-4. Chinese.