产品说明书
Cornuside
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同义名 : | - |
| CAS号 : | 131189-57-6 | |
| 货号 : | A1371131 | |
| 分子式 : | C24H30O14 | |
| 纯度 : | 98% | |
| 分子量 : | 542.487 | |
| MDL号 : | MFCD21606970 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(193.55 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Cornuside, a natural product isolated and purified from the fruits of Cornus officinalis Sieb. et Zucc. with immunomodulatory and anti-inflammatory activities, suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells, treats myocardial I/R and protect the liver from CCl₄-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses, and has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.84mL 0.37mL 0.18mL |
9.22mL 1.84mL 0.92mL |
18.43mL 3.69mL 1.84mL |
| 参考文献 |
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