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Aescin A

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Chemical Structure| 123748-68-5 同义名 : Escin IA
CAS号 : 123748-68-5
货号 : A1371128
分子式 : C55H86O24
纯度 : 98%
分子量 : 1131.257
MDL号 : MFCD10566608
存储条件:

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(92.82 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Escin IA is the main active ingredient of the saponin fraction of Aesculus chinensis Bunge fruits (SFAC) for the anti-TNBC metastasis activity, and its action mechanisms involved inhibition of EMT process by down-regulating LOXL2 expression.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

0.88mL

0.18mL

0.09mL

4.42mL

0.88mL

0.44mL

8.84mL

1.77mL

0.88mL

参考文献

[1]Yang XW, Zhao J, et al. [Studies on the biotransformation of escin Ia by human intestinal bacteria and the anti-tumor activities of desacylescin I] . Beijing Da Xue Xue Bao. 2004 Feb;36(1):31-5. Chinese.