产品说明书

	同义名 :	-
	CAS号 :	2086257-77-2
	货号 :	A1364932
	分子式 :	C21H23ClF3N3O3
	纯度 :	99%+
	分子量 :	457.874
	MDL号 :	MFCD32663268
	存储条件：	粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	VBIT-4 inhibits the oligomerization of voltage-dependent anion channel 1 (VDAC1) with a binding affinity (Kd) of 17 μM. As an inhibitor of apoptosis, it has potential therapeutic applications in conditions associated with apoptosis, including neurodegenerative and cardiovascular diseases [1].

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.18mL 0.44mL 0.22mL	10.92mL 2.18mL 1.09mL	21.84mL 4.37mL 2.18mL

参考文献
[1]Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.