产品说明书

hDHODH-IN-1

Print
Chemical Structure| 1173715-42-8 同义名 : -
CAS号 : 1173715-42-8
货号 : A1364873
分子式 : C17H14N2O2
纯度 : 99%+
分子量 : 278.305
MDL号 : MFCD32671346
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(898.29 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 hDHODH-IN-1, a human dihydroorotate dehydrogenase (hDHODH) inhibitor, exhibits anti-inflammatory effects [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.59mL

0.72mL

0.36mL

17.97mL

3.59mL

1.80mL

35.93mL

7.19mL

3.59mL
参考文献

[1]Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9(2):e87960.