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Caffeic Acid

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Chemical Structure| 331-39-5 同义名 : 3,4-Dihydroxycinnamic Acid
CAS号 : 331-39-5
货号 : A134210
分子式 : C9H8O4
纯度 : 98%
分子量 : 180.157
MDL号 : MFCD00004392
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(582.82 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00065715 Common Cold Phase 3 Completed - United States, Wisconsin ... 展开 >> University of Wisconsin-Madison Department of Family Medicine Madison, Wisconsin, United States, 53706-1490 收起 <<
NCT02050334 Healthy Phase 1 Completed - United States, Indiana ... 展开 >> IU Health Neuroscience Center Indianapolis, Indiana, United States, 46202 收起 <<
NCT02050334 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.55mL

1.11mL

0.56mL

27.75mL

5.55mL

2.78mL

55.51mL

11.10mL

5.55mL

参考文献

[1]Pradhananga S, et al. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice. Eur J Pharmacol. 2015 Sep 5;762:313-21.

[2]Liang G, et al. The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats. Behav Brain Funct. 2015 Apr 18;11:18.