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Py-BODIPY-NHS ester

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Chemical Structure| 201998-61-0 同义名 : -
CAS号 : 201998-61-0
货号 : A1339770
分子式 : C20H17BF2N4O4
纯度 : 98%+
分子量 : 426.181
MDL号 : MFCD32858277
存储条件:

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 25 mg/mL(58.66 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 BODIPY dye, known for its strong ultraviolet absorption, has a sharp fluorescence peak and high quantum yield, maintaining stability under various physiological conditions without significant sensitivity to environmental polarity or pH[1]. BODIPY, due to its structural asymmetry, yields various structural derivatives. Its lipid droplet dyes can permeate cell membranes to localize and specifically stain polar lipids within cells, making them suitable for labeling both live and fixed cells[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.23mL

11.73mL

2.35mL

1.17mL

23.46mL

4.69mL

2.35mL

参考文献

[1]Kamkaew A, et al. BODIPY dyes in photodynamic therapy. Chem Soc Rev. 2013 Jan 7;42(1):77-88.

[2]Vasta JD, et al. Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of CellularATP on Target Engagement. Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11.