Calcipotriol

产品说明书

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Chemical Structure| 112965-21-6 同义名 : MC 903;Calcipotriene;Sorilux.;Psorcutan;PRI 2201;Dovonex;Daivonex;CCRIS 7700;Calcitrene;Calciptriol
CAS号 : 112965-21-6
货号 : A133174
分子式 : C27H40O3
纯度 : 98+%
分子量 : 412.605
MDL号 : MFCD00866630
存储条件:

Pure form Keep in dark place,Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(254.48 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

无水乙醇: 45 mg/mL(109.06 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.42mL

0.48mL

0.24mL

12.12mL

2.42mL

1.21mL

24.24mL

4.85mL

2.42mL

参考文献

[1]Sakabe J, Umayahara T, et al. Calcipotriol increases hCAP18 mRNA expression but inhibits extracellular LL37 peptide production in IL-17/IL-22-stimulated normal human epidermal keratinocytes. Acta Derm Venereol. 2014 Sep;94(5):512-6.

[2]Al-Jaderi Z, Maghazachi AA. Effects of vitamin D3, calcipotriol and FTY720 on the expression of surface molecules and cytolytic activities of human natural killer cells and dendritic cells. Toxins (Basel). 2013 Oct 28;5(11):1932-47.