SIRT2-IN-8

产品说明书

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Chemical Structure| 115687-05-3 同义名 : -
CAS号 : 115687-05-3
货号 : A1328377
分子式 : C20H17ClN4O3
纯度 : 97%
分子量 : 396.827
MDL号 : MFCD02039810
存储条件:

Pure form Keep in dark place,Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(126 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 SIRT2-IN-8 is a potent SIRT2 inhibitor. SIRT2-IN-8 can be used in the study of Huntington's and Parkinson's diseases[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.52mL

0.50mL

0.25mL

12.60mL

2.52mL

1.26mL

25.20mL

5.04mL

2.52mL

参考文献

[1]Bodner RA, Outeiro TF, Altmann S, et al. Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. Proc Natl Acad Sci U S A. 2006;103(11):4246-4251.