产品说明书

Benzocaine

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Chemical Structure| 94-09-7 同义名 : 苯唑卡因;对氨基苯甲酸乙酯;4-氨基苯甲酸乙酯;乙基-4-氨基苯甲酸酯;4-氨基苯甲酸乙酯 ;Ethyl 4-Aminobenzoate;NSC 41531;NSC 4688;H-4-Abz-OEt
CAS号 : 94-09-7
货号 : A132131
分子式 : C9H11NO2
纯度 : 98%
分子量 : 165.189
MDL号 : MFCD00007892
存储条件:

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(635.64 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 2 mg/mL(12.11 mM),配合低频超声,并水浴加热至45℃助溶

动物实验配方:
生物活性
靶点
  • Sodium Channel

描述 Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.05mL

1.21mL

0.61mL

30.27mL

6.05mL

3.03mL

60.54mL

12.11mL

6.05mL

参考文献

[1]Pinto LM, Yokaichiya DK, et al. Interaction of benzocaine with model membranes. Biophys Chem. 2000 Oct 30;87(2-3):213-23.

[2]Wang GK, Quan C, Wang S. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435(2):293-302.