产品说明书

EP2 receptor antagonist-2

Print
Chemical Structure| 615273-95-5 同义名 : -
CAS号 : 615273-95-5
货号 : A1282149
分子式 : C15H14F3N3O
纯度 : 99%+
分子量 : 309.286
MDL号 : -
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(387.99 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 EP2 receptor antagonist-2 (CID891729), an EP2 receptor antagonist, blocks the activation of the EP2 receptor triggered by PGE2 and additionally diminishes lactate dehydrogenase (LDH) release instigated by N-methyl-D-aspartate (NMDA)[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.23mL

0.65mL

0.32mL

16.17mL

3.23mL

1.62mL

32.33mL

6.47mL

3.23mL
参考文献

[1]Jiang J, et al. Discovery of 2-Piperidinyl Phenyl Benzamides and Trisubstituted Pyrimidines as Positive Allosteric Modulators of the Prostaglandin Receptor EP2. ACS Chem Neurosci. 2018 Apr 18;9(4):699-707.