产品说明书

Fusidine

Print
Chemical Structure| 6990-06-3 同义名 : Fusidate;SQ-16603;CEM-102;Fucidine;Fucidin;Anhydrous Fusidic Acid;Fusidic acid
CAS号 : 6990-06-3
货号 : A127938
分子式 : C31H48O6
纯度 : 97%
分子量 : 516.709
MDL号 : MFCD00865135
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(203.21 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum, is categorized within the steroid class but lacks corticosteroid effects. It works by inhibiting bacterial growth by preventing the release of translation elongation factor G (EF-G) from the ribosome[1].[2].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02025309 Neuromuscular Monitoring ... 展开 >> Sugammadex Effect 收起 << Phase 4 Completed - Turkey ... 展开 >> Ankara University Faculty of Medicine, Ibni Sina Hospital OR Ankara, Turkey, 06700 收起 <<
NCT03378427 Prosthetic Joint Infection Not Applicable Recruiting January 15, 2020 France ... 展开 >> GHU Garches Recruiting Garches, France, 92380 Contact: Aurélien DINH, M.D.    +33 (0)1 47 10 77 58    aurelien.dinh@aphp.fr    Hôpital de la Croix Rousse Recruiting Lyon, France, 69004 Contact: Tristan FERRY, M.D. Ph. D.    +33 (0)4 72 07 17 55    tristan.ferry@univ-lyon1.fr 收起 <<
NCT02123628 Diabetes Mellitus Phase 4 Completed - France ... 展开 >> Dron Hospital Tourcoing, Nord, France, 59200 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.94mL

0.39mL

0.19mL

9.68mL

1.94mL

0.97mL

19.35mL

3.87mL

1.94mL

参考文献

[1]Curbete MM, et al. A Critical Review of the Properties of Fusidic Acid and Analytical Methods for Its Determination. Crit Rev Anal Chem. 2016;46(4):352-360.

[2]Payne AJ, et al. Fusidic acid is an effective treatment against Toxoplasma gondii and Listeria monocytogenes in vitro, but not in mice. Parasitol Res. 2013;112(11):3859-3863.