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10,11-Dihydrocarbamazepine

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Chemical Structure| 3564-73-6 同义名 : 双氢卡马西平
CAS号 : 3564-73-6
货号 : A127850
分子式 : C15H14N2O
纯度 : 99%+
分子量 : 238.285
MDL号 : MFCD00005072
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(440.65 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine and also serves as an intermediate in its metabolism. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine, which is believed to contribute to its anticonvulsant efficacy[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.20mL

0.84mL

0.42mL

20.98mL

4.20mL

2.10mL

41.97mL

8.39mL

4.20mL
参考文献

[1]Courtney Hunek, et al. Measurement of 10,11-dihydro-10-hydroxy-carbamazepine in serum and plasma by high-performance liquid chromatography. Clin Chem Lab Med. 2008;46(10):1429-33.