产品说明书

Chimmitecan

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Chemical Structure| 185425-25-6 同义名 : (S)-9-Allyl-10-Hydroxycamptothecin
CAS号 : 185425-25-6
货号 : A1272584
分子式 : C23H20N2O5
纯度 : 99%+
分子量 : 404.415
MDL号 : MFCD28138424
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(296.72 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Chimmitecan, a novel 9-small alkyl-substituted lipophilic camptothecin, is a potent inhibitor of topoisomerase I and has anticancer activity[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.47mL

0.49mL

0.25mL

12.36mL

2.47mL

1.24mL

24.73mL

4.95mL

2.47mL
参考文献

[1]Huang M, et, al. Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. Clin Cancer Res. 2007 Feb 15;13(4):1298-307.